Martin Widschwendter lectures on the use of epigenetic-based WID®-Tests, in primary and secondary cancer prevention
Topics covered are:
- Unmet needs in cancer prevention
- P4-medicine
- The rationale for utilizing DNA-methylation for cancer risk prediction
- The principle of epigenetic-based risk prediction in surrogate tissue
- Cell type specificity (epithelial cells vs immune cells)
- Responsiveness to risk factors (e.g., progesterone in breast cancer)
- The rationale for cervical smear samples vs. blood or buccal swab
- Embryological considerations
- The WID®-Sola for the risk prediction/stratification of four women’s cancers (cervical, endometrial, ovarian and breast cancer)
- Monitoring preventive measures (e.g., mifepristone for breast cancer)
- WID®-easy and WID®-qCIN (aka “WID®-can”) for the early detection of endometrial cancer and preinvasive cervical cancer
- Monitoring hormone replacement therapy using WID®-REA
- Monitoring preventive measures for healthy aging and longevity using epigenetic signatures
- Personalized pan-cancer prevention